5 FLUOROURACIL TOXICITY (DPD GENE MUTATION)
5-Fluorouracil (5-FU) is a commonly used anticancer drug. It functions by irreversibly inhibiting thymidylate synthase. 5-FU is widely used in a number of cancers worldwide. Detoxification of 5-FU is mediated by the dihydropyrimidine dehydrogenase (DPD) gene . Apart from 5-FU, the gene also is involved in detoxification of Capecitabine, and Tegafur. Genetic variations in the gene can cause a partial or complete deficiency of function, which may lead to severe drug toxicity.
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Report Frequency: Sample Mon by 11 am; Report Fri
Special Instruction: Physician prescription is mandatory.
Price : ₹ 7600.00
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- 5 FLUOROURACIL TOXICITY (DPD GENE MUTATION)