FISH - BCR / ABL or Philadelphia translocation
The t(9;22) is a balanced translocation between chromosomes 9 & 22 leading to fusion of bcr & c-abl genes and to the transcription of leukemia specific bcr-abl mRNAs. Philadelphia (Ph) chromosome causing the BCR/ABL fusion, is present in approximately 95% cases of Chronic myeloid leukemia (CML) and 25-30% cases of Acute lymphoblastic leukemia (ALL). Due to development of potent tyrosine kinase inhibitors & anti-sense therapies, presence of BCR/ABL translocation is a favorable prognostic marker.
Parameter(s) covered : 2
Report Frequency: Sample Daily by 4 pm; Report 4 Working days
Special Instruction: Duly filled Chromosome & FISH analysis Requisition Form (Form 17) is mandatory.
Price : ₹ 4400.00
Parameters
- Send Out Comment
- Vip_Fish