FISH-POSITIVE SELECTION OF CD138 CELLS IN MULTIPLE MYELOMA (6 PROBES)
Conventional Cytogenetics detects abnormal karyotype in 40% newly diagnosed Myeloma cases. Based on conventional karyotyping there are two prognostic groups: Hyperdiploid (48-75 chromosomes ) associated with favourable prognosis and Non-hyperdiploid (<48 & >75 chromosomes) associated with an unfavourable prognosis. Abnormalities detected by FISH after positive selection of CD138 cells, has predictive usefulness namely- High risk disease: if t(14:16), t(14;20), del17p & del1p detected; Standard risk disease: if t(11:14), t(6;14) &/or trisomies detected; Intermediate risk: if t(4;14) & gain(1q21) detected. FISH is performed after positive selection of CD138 cells thereby providing more accurate results.
Parameter(s) covered : 2
Report Frequency: Sample Daily by 4 pm; Report 4 Working days
Special Instruction: Duly filled Chromosome & FISH analysis Requisition Form (Form 17) is mandatory.
Price : ₹ 14000.00
Parameters
- Multiple Myeloma Panel_A
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