t(1;19) (q23;p13.3); TCF3- BX1(E2A-PBX1), PCR QUALITATIVE
Chromosomal rearrangements can produce tumorigenic fusion genes. This mechanism is seen in 15-25% of Leukemias, Lymphomas & Sarcomas. Fusions can be produced by translocations, inversions or deletions. Specific gene fusions in a patient's tumor cells have an important bearing on the management & prognosis. Detection of translocation t(1;19) in Acute Lymphoblastic leukemia (ALL) may be balanced or unbalanced. Both are associated with poor prognosis but more so if you have an unbalanced translocation. Such patients are usually children with T-ALL and require intensive chemotherapy to control the disease.
Parameter(s) covered : 1
Report Frequency: Sample Mon / Thu by 11 am; Report Wed / Sat
Special Instruction: Physician prescription is mandatory.
Price : ₹ 3500.00
Parameters
- t (1;19) (q23 ;p13.3); TCF3-PBX1(E2A- PBX1)