THROMBOPHILIA TOTAL PROFILE
Thrombophilia evaluations are usually performed to assess the need to extend anticoagulation, hence testing should be performed in a steady state, remote from the acute event. Laboratory assays to detect thrombophilic states include highly sensitive and specific test like molecular diagnosis, immunologic and functional assays. Many coagulation factors and inhibitors are affected during acute thrombosis, acute illnesses, inflammatory conditions, pregnancy & certain medications. Antithrombin is decreased by heparin and acute thrombosis whereas protein C & S levels are increased during acute thrombosis, but decreased by Warfarin. Antiphospholipid antibodies like lupus anticoagulants, anti cardiolipin antibodies & anti beta 2 glycoprotein antibodies are also associated with thromboembolic disease states. Higher levels of factor VIII (>150%), factor V leiden mutations and increased homocysteine levels are also associated with increased risk of thromboembolic disease.
Parameter(s) covered : 23
Report Frequency: Sample Mon / Thu by 9 am; Report
Wed / Sat
Special Instruction: Overnight fasting is preferred. Duly filled Coagulation Requisition Form (Form 15) is mandatory. It is recommended that patient discontinues Heparin for 1 day and Oral Anticoagulants for 7 days prior to sampling as these drugs may affect test
results. Discontinuation should be with prior consent from the treating Physician.
Price : ₹ 23200.00
Parameters
- Antithrombin Activity
- Beta 2 glycoprotein IgM
- Beta 2 glycoprotein IgG
- Cardiolipin Antibody, IgG
- Cardiolipin Antibody, IgM
- Control Value
- Factor V Leiden Mutation
- Factor VIII Functional
- FIBRINOGEN
- Homocysteine
- INTERPRETATION
- LUPUS ANTICOAGULANT BY dRVVT New
- Mix Ratio
- MIXING STUDIES
- MTHFR gene Mutation
- NORMALISED RATIO
- PARTIAL THROMBOPLASTIN TIME-LUPUS ANTICOAGULANT SP
- Patient Plasma : PNP (1:1) Mix Value
- Patient Value
- Protein C , Functional
- PROTEIN S (FREE) ANTIGEN
- Prothrombin gene Mutation
- Screen Ratio