t(4;11) (q21;q23); (MLL-AF4), PCR QUALITATIVE
Chromosomal rearrangements can produce tumorigenic fusion genes. This mechanism is seen in 15-25% of Leukemias, Lymphomas & Sarcomas. Fusions can be produced by translocations, inversions or deletions. Specific gene fusions in a patient's tumor cells have an important bearing on the management & prognosis. This translocation results in the MLL- AF4 fusion gene and is associated with a poor outcome. It is found in >80% cases of infant ALL and is the most frequent MLL translocation in ALL but is rarely seen in AML.
Parameter(s) covered : 1
Report Frequency: Sample Mon / Thu by 11 am; Report Wed / Sat
Special Instruction: Physician prescription is mandatory.
Price : ₹ 3500.00
Parameters
- t (4;11) (q21;q23); (MLL-AF4)